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1

Overlap in Virus Specificity Leads to the Discovery of Small Molecules Active Against Rabies Virus, Cytomegalovirus, and Monkey Pox Virus

Vishwanath R. Lingappa, Usha Lingappa, Eva Borst, Jacqueline Pajda, Ian Brown, Scott Long, Bhadresh Rami, Aysegul Nalca, W. Ian Lipkin, Charles Rupprecht, Martin Messerle, Clarence R. Hurt, William Ha

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 95 KB

english, 2010

2

10.1038/45574

Lingappa, Vishwanath R., Hegde, Ramanujan S., Tremblay, Patrick, Groth, Darlene, DeArmond, Stephen J., Prusiner, Stanley B.

Journal:

Year:

1999

Language:

english

File:

PDF, 299 KB

english, 1999

3

Mechanism of Protein Translocation Across the Endoplasmic Reticulum Membrane

Walter, Peter, Lingappa, Vishwanath R.

Journal:

Annual Review of Cell Biology

Year:

1986

Language:

english

File:

PDF, 526 KB

english, 1986

4

Validation of a cell-based ELISA as a screening tool identifying anti-alphavirus small-molecule inhibitors

Spurgers, Kevin B., Hurt, Clarence R., Cohen, Jeffrey W., Eccelston, Lori T., Lind, Cathleen M., Lingappa, Vishwanath R., Glass, Pamela J.

Journal:

Journal of Virological Methods

Year:

2013

Language:

english

File:

PDF, 541 KB

english, 2013

5

A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane

Mize, Nancy K., Andrews, David W., Lingappa, Vishwanath R.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.57 MB

english, 1986

6

The formation of RNA granule-derived capsid assembly intermediates appears to be conserved between HIV-1 and the non-primate lentivirus FIV

Reed, Jonathan C., Westergreen, Nick, Barajas, Brook C., Ressler, Dylan T.B., Phuong, Daryl J., Swain, John V., Lingappa, Vishwanath R., Lingappa, Jaisri R.

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 2.95 MB

english, 2018

7

Conformational control through translocational regulation: a new view of secretory and membrane protein folding

Vishwanath R. Lingappa, D. Thomas Rutkowski, Ramanujan S. Hegde, Olaf S. Andersen

Journal:

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

8

Chicken ovalbumin contains an internal signal sequence

Lingappa, Vishwanath R., Lingappa, Jaisri R., Blobel, Günter

Journal:

Year:

1979

File:

PDF, 712 KB

1979

9

Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein

Yost, C. Spencer, Lopez, Charles D., Prusiner, Stanley B., Myers, Rchard M, Lingappa, Vishwanath R.

Journal:

Year:

1990

File:

PDF, 539 KB

1990

10

New variation on the translocation of proteins during early biogenesis of apolipoprotein B

Chuck, Steven L., Yao, Zemin, Blackhart, Brian D., McCarthy, Brian J., Lingappa, Vishwanath R.

Journal:

Year:

1990

File:

PDF, 435 KB

1990

11

Rapid regulation of steroidogenesis by mitochondrial protein import

Bose, Himangshu S., Lingappa, Vishwanath R., Miller, Walter L.

Journal:

Year:

2002

Language:

english

File:

PDF, 480 KB

english, 2002

12

Control of protein topology at the endoplasmic reticulum

Vishwanath R. Lingappa

Journal:

Cell Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 940 KB

english, 1991

13

Identification and Characterization of a Hepatitis C Virus Capsid Assembly Inhibitor

Juliane Gentzsch, Clarence R. Hurt, Vishwanath R. Lingappa, Thomas Pietschmann

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

14

Evidence for Host Drug Targets Essential for Dengue Virus Capsid Formation

Marissa Baker-Wagner, Nicole Wolcott, Yoko Marwidi, Shao Feng Yu, Debendranath Dey, Bruce Onisko, Katie Barlow, Shalini Potluri, Christine Sahlman, Alfredo Calayag, Vishwanath R. Lingappa, Pamela Glas

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

15

Small Molecule Inhibitors of De Novo Cell-free Capsid Assembly Effective against Flaviviridae and Togaviridae

Vishwanath R. Lingappa, Juliane Gentzsch, Kiel Copeland, I.-ting Jaing, Michael Corpuz, Pamela Glass, Jaisri R. Lingappa, Brenna Kelley-Clarke, Debendranath Dey, Colm Kelleher, Andy Atuegbu, Amy Ander

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

16

Cell-Free Protein Synthesizing Systems As Tools for Discovery of Drugs Inhibiting Viral Capsid Assembly

Vishwanath R. Lingappa, Emma Harrell, Kiel Copeland, M. Dharma Prasad, Vinod Asundi, Nick Hahner, Jean Francis, Debendranath Dey, Jennifer Welsh, Amanda Macieik, Jaisri R. Lingappa, Colm Kelleher, Cla

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

17

The Discovery and Efficacy of a Small Molecule Inhibitor of Ebola Capsid Assembly in an Animal Model

Jean Francis, Warren Kalina, Travis Warren, Katie Edwards, I-ting Jaing, A. Pia Abola, Abhar Nissar, Anatoliy Kitaygorodskyy, Clarence R. Hurt, Sina Bavari, William Hansen, Vishwanath R. Lingappa

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 90 KB

english, 2010

18

Regulation of protein biogenesis at the endoplasmic reticulum membrane

Ramanujan S Hegde, Vishwanath R Lingappa

Journal:

Trends in Cell Biology

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

19

Developmental expression of prion protein gene in brain

Michael P. McKinley, Bruce Hay, Vishwanath R. Lingappa, Ivan Lieberburg, Stanley B. Prusiner

Journal:

Developmental Biology

Year:

1987

Language:

english

File:

PDF, 2.07 MB

english, 1987

20

Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism

Jens Lutz, Christine Brabeck, Hartmut H. Niemann, Ulrich Kloz, Carsten Korth, Vishwanath R. Lingappa, Alexander Bürkle

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 783 KB

english, 2010

21

Membrane Protein Biogenesis: Regulated Complexity at the Endoplasmic Reticulum

Ramanujan S. Hegde, Vishwanath R. Lingappa

Journal:

Year:

1997

Language:

english

File:

PDF, 94 KB

english, 1997

22

Sequence-Specific Alteration of the Ribosome–Membrane Junction Exposes Nascent Secretory Proteins to the Cytosol

Ramanujan S Hegde, Vishwanath R Lingappa

Journal:

Year:

1996

Language:

english

File:

PDF, 520 KB

english, 1996

23

TRAM Regulates the Exposure of Nascent Secretory Proteins to the Cytosol during Translocation into the Endoplasmic Reticulum

Ramanujan S Hegde, Sabine Voigt, Tom A Rapoport, Vishwanath R Lingappa

Journal:

Year:

1998

Language:

english

File:

PDF, 273 KB

english, 1998

24

Regulation of Protein Topology by trans-Acting Factors at the Endoplasmic Reticulum

Ramanujan S. Hegde, Sabine Voigt, Vishwanath R. Lingappa

Journal:

Year:

1998

Language:

english

File:

PDF, 235 KB

english, 1998

25

SIGNAL SEQUENCES FOR EARLY EVENTS IN PROTEIN SECRETION AND MEMBRANE ASSEMBLY

Vishwanath R. Lingappa, Jaisri R. Lingappa, Günter Blobel

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 357 KB

english, 1980

26

More than just a channel: Provocative new features of protein traffic across the ER membrane

Vishwanath R. Lingappa

Journal:

Year:

1991

Language:

english

File:

PDF, 428 KB

english, 1991

27

Pause transfer: A topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation

Steven L. Chuck, Vishwanath R. Lingappa

Journal:

Year:

1992

Language:

english

File:

PDF, 2.93 MB

english, 1992

28

A stop transfer sequence confers predictable transmembrane orientation to a previously secreted protein in cell-free systems

Spencer Yost, C., Hedgpeth, Joe, Lingappa, Vishwanath R.

Journal:

Year:

1983

Language:

english

File:

PDF, 2.72 MB

english, 1983

29

[Part 1: Biological Sciences] || Determinants for Protein Localization: β -Lactamase Signal Sequence Directs Globin across Microsomal Membranes

Vishwanath R. Lingappa, Jeffery Chaidez, C. Spencer Yost and Joe Hedgpeth

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.16 MB

english, 1984

30

Biogenesis of the Platelet Receptor for Fibrinogen: Evidence for Separate Precursors for Glycoproteins IIb and IIIa

Paul F. Bray, Jean-Philippe Rosa, Vishwanath R. Lingappa, Yuet W. Kan, Rodger P. McEver and Marc A. Shuman

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.04 MB

english, 1986

31

Expression of Receptors for Cholecystokinin and Other Ca2+-Mobilizing Hormones in Xenopus Oocytes

John A. Williams, Dennis J. McChesney, M. Clara Calayag, Vishwanath R. Lingappa and Craig D. Logsdon

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 931 KB

english, 1988

32

Nascent Prehormones are Intermediates in the Biosynthesis of Authentic Bovine Pituitary Growth Hormone and Prolactin

Vishwanath R. Lingappa, Anne Devillers-Thiery and Günter Blobel

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.26 MB

english, 1977

33

Membrane Assembly in vitro: Synthesis, Glycosylation, and Asymmetric Insertion of a Transmembrane Protein

Flora N. Katz, James E. Rothman, Vishwanath R. Lingappa, Günter Blobel and Harvey F. Lodish

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.55 MB

english, 1977

34

Coupled Cell-Free Synthesis, Segregation, and Core Glycosylation of a Secretory Protein

Vishwanath R. Lingappa, Jaisri R. Lingappa, Rajani Prasad, Kurt E. Ebner and Gunter Blobel

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 1.01 MB

english, 1978

35

Tryptic Dissection and Reconstitution of Translocation Activity for Nascent Presecretory Proteins across Microsomal Membranes

Peter Walter, Robert C. Jackson, Madeleine M. Marcus, Vishwanath R. Lingappa and Günter Blobel

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.60 MB

english, 1979

36

Cell-Free Synthesis and Segregation of β2-Microglobulin

Vishwanath R. Lingappa, Bruce A. Cunningham, S. Michal Jazwinski, Thomas P. Hopp, Gunter Blobel and Gerald M. Edelman

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 985 KB

english, 1979

37

Part 1 || Nascent Chicken Ovalbumin Contains the Functional Equivalent of a Signal Sequence

Vishwanath R. Lingappa, Dennis Shields, Savio L. C. Woo and Günter Blobel

Journal:

The Journal of Cell Biology

Year:

1978

Language:

english

File:

PDF, 991 KB

english, 1978

38

Translocation of Globin Fusion Proteins across the Endoplasmic Reticulum Membrane in Xenopus laevis Oocytes

Kay Simon, Eve Perara and Vishwanath R. Lingappa

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 2.24 MB

english, 1987

39

Expression of Human Cathepsin D in Xenopus Oocytes: Phosphorylation and Intracellular Targeting

Phyllis L. Faust, Doris A. Wall, Eve Perara, Vishwanath R. Lingappa and Stuart Kornfeld

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 1.10 MB

english, 1987

40

Part 1 || Secreted Hepatitis B Surface Antigen Polypeptides Are Derived from a Transmembrane Precursor

Kay Simon, Vishwanath R. Lingappa and Don Ganem

Journal:

The Journal of Cell Biology

Year:

1988

Language:

english

File:

PDF, 676 KB

english, 1988

41

Evidence for a Two-Step Mechanism Involved in Assembly of Functional Signal Recognition Particle Receptor

David W. Andrews, Leander Lauffer, Peter Walter and Vishwanath R. Lingappa

Journal:

The Journal of Cell Biology

Year:

1989

Language:

english

File:

PDF, 3.88 MB

english, 1989

42

A Former Amino Terminal Signal Sequence Engineered to an Internal Location Directs Translocation of Both Flanking Protein Domains

Eve Perara and Vishwanath R. Lingappa

Journal:

The Journal of Cell Biology

Year:

1985

Language:

english

File:

PDF, 2.59 MB

english, 1985

43

Biogenesis and Transmembrane Topology of the CHIP28 Water Channel at the Endoplasmic Reticulum

William R. Skach, Lan-bo Shi, M. Clara Calayag, Antonio Frigeri, Vishwanath R. Lingappa and A. S. Verkman

Journal:

The Journal of Cell Biology

Year:

1994

Language:

english

File:

PDF, 3.59 MB

english, 1994

44

A Eukaryotic Cytosolic Chaperonin Is Associated with a High Molecular Weight Intermediate in the Assembly of Hepatitis B Virus Capsid, a Multimeric Particle

Jaisri R. Lingappa, Robert L. Martin, Mei Lie Wong, Don Ganem, William J. Welch and Vishwanath R. Lingappa

Journal:

The Journal of Cell Biology

Year:

1994

Language:

english

File:

PDF, 1.39 MB

english, 1994

45

Signal Sequences Influence Membrane Integration of the Prion Protein †

Ott, Carolyn M., Lingappa, Vishwanath R.

Journal:

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

46

Evidence for a secretory form of the cellular prion protein

Hay, Bruce, Prusiner, Stanley B., Lingappa, Vishwanath R.

Journal:

Year:

1987

Language:

english

File:

PDF, 2.97 MB

english, 1987

47

Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets

Marreiros, Rita, Müller-Schiffmann, Andreas, Bader, Verian, Selvarajah, Suganya, Dey, Debendranath, Lingappa, Vishwanath R., Korth, Carsten

Journal:

Year:

2014

Language:

english

File:

PDF, 802 KB

english, 2014

48

Exocyst Sec10 Is Involved in Basolateral Protein Translation and Translocation in the Endoplasmic Reticulum

Choi, Soo Young, Fogelgren, Ben, Zuo, Xiaofeng, Huang, Liwei, McKenna, Sarah, Lingappa, Vishwanath R., Lipschutz, Joshua H.

Journal:

Nephron Experimental Nephrology

Year:

2012

Language:

english

File:

PDF, 525 KB

english, 2012

49

Carbonic Anhydrase I Is Recognized by an SOD1 Antibody upon Biotinylation of Human Spinal Cord Extracts

Liu, Jian, Akhavan, Armin, Lu, Mengde, Gruzman, Arie, Lingappa, Vishwanath R., An, Jiyan, Bowser, Robert

Journal:

International Journal of Molecular Sciences

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

50

California's Proposition 186: Lessons from a Single-Payer Health Care Reform Ballot Initiative Campaign

Krista Farey and Vishwanath R. Lingappa

Journal:

Journal of Public Health Policy

Year:

1996

Language:

english

File:

PDF, 2.03 MB

english, 1996